The Holy Spirit & Mary, Mother of Jesus: when the Holy Spirit came upon Mary, did she then have the Holy Spirit as we do? [Acts 1, Acts 2:17, Psalm 51:11, John 7:39]. The Holy Spirit in The Old Testament: Can you clarify the Spirit coming upon people in the Old Testament and if He would then stay with them? Hail Mary, Full of Grace: What does it mean to say, "Hail Mary, full of grace?" Does it mean she was born sinless?