Addressing Jesus or the Holy Spirit in Our Prayers: Is it acceptable to address Jesus in prayer, or are we disobeying him to not address God directly? [John 16:23-26, Acts 4:25-30, Ephesians 3:14, Matthew 7:11, Matthew 6:9-13], Luke 11:13, Revelation 22:20, Acts 7:59, Ezekiel 37:9].